Paraneoplastic Leser-Trélat Syndrome: Clinical Manifestations, Diagnosis and Treatment

Examination of the skin is a widely available and simple method examining patient, which nevertheless allows you to diagnose systemic disorders diseases in human body at an early stage. A doctor any specialty may encounter dermatological paraneoplastic syndromes his practice, are group associated with malignant neoplasms, but not directly related primary tumor or its metastases. Timely analysis makes it possible suspect tumors that cause them urgently refer patient oncologist for purpose diagnosis treatment potentially curable oncological disease. In clinical Leser-Trélat syndrome very common, manifested by sudden appearance multiple seborrheic keratomas (mainly back abdomen) increase their number size over short period time (weeks, months). Treatment this can be carried out both simultaneously after underlying Dermatological require further in-depth study understand pathogenesis, create clear classification develop algorithms doctor’s actions case detection.